About us


Country: United States of America
Languages: English, Hindi, Gujarati, Marathi
Research interests: NMR metabolomics, in-cell NMR, small GTPases, cardiac and cancer metabolism
Research overview: I obtained my PhD in Chemistry from the University of Nebraska-Lincoln. Under the guidance of Dr. Robert Powers, I developed new methods to better understand cellular metabolism at the metabolite level and determined how disease states affected the cellular environment. I applied my training on a wide array of disease states: drug resistance in pancreatic cancer cells, antibacterial-resistant infections, and studying cell-cell communication at the metabolite level. I developed the necessary skills required to probe out details of how cellular environments change due to disease progression, stress, and pharmacological interventions. To gain a complete picture of the cellular environment, both at small molecule and macromolecular level, I joined Dr. Angela Gronenborn’s group at the University of Pittsburgh. As a structural biologist my current research involves characterization of protein structures, protein-protein, and protein-ligand interactions.

Research Highlights:
(2021) H. E. Roth+, F. Bhinderwala+, R. Franco, Y. Zhou, and R. Powers* (2021) “DNAJA1 dysregulates metabolism promoting an anti-apoptotic phenotype in pancreatic ductal adenocarcinoma”Journal of Proteome Research, 20(8):3925-3939; https://doi.org/10.1021/acs.jproteome.1c00233

(2018) T. Gebregiworgis, F. Bhinderwala, V. Purohit, N. V. Chaika, P. K. Singh, and R. Powers* “Insights into Gemcitabine Resistance and the Potential for Therapeutic Monitoring”Metabolomics, 14:156 PMC6620022   

(2022) W. Zhu, A.J. Guseman, F. Bhinderwala, M. Lu, A. M. Gronenborn. Visualizing globular proteins in mammalian cells using 19F NMR, Angew. Chem. Int. Ed., e202201097

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