Glauce
Country: Brazil
Languages: Portuguese, English
Research interests: nuclear magnetic resonance, intrinsically disordered proteins, dynamics, structure in solution, nucleocapsid assembly
Research overview: I am interested in understanding the role of the intrinsically disordered N-terminal region in solution structure and dynamics of flaviviruses capsid proteins. Besides of that, I would like to understand the nucleocapsid assembly and the role of the intrinsically disordered N-terminal region and α4/α4’ helix in this process.
Research Highlights:
(2022) The interaction of dengue virus capsid protein with negatively charged interfaces drives the in vitro assembly of nucleocapsid-like particles. Mebus-Antunes, Nathane C.; Ferreira, Wellington S.; Barbosa, Glauce M.; Neves-Martins, Thais C.; Weissmuller, Gilberto; Almeida, Fabio C. L.; Da Poian, Andrea T. PLoS One, 17:e0264643. https://doi.org/10.1371/journal.pone.0264643
(2022) Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids. Caruso, Icaro P.; Dos Santos Almeida, Vitor; Do Amaral, Mariana J.; De Andrade, Guilherme C.; De Araújo, Gabriela R.; De Araújo, Talita S.; De Azevedo, Jéssica M.; Barbosa, Glauce M.; Bartkevihi, Leonardo; Bezerra, Peter R.; Dos Santos Cabral, Katia M; et al. International Journal Of Biological Macromolecules. 203:466-480. https://doi.org/10.1016/j.ijbiomac.2022.01.121
(2021) The 1H, 15N, and 13C resonance assignments of the N-terminal domain of the nucleocapsid protein from the Middle East respiratory syndrome coronavirus. De Araujo, Talita S.; Barbosa, Glauce M.; Sanches, Karoline; Azevedo, Jéssica M.; Dos Santos Cabral, Katia M.; Almeida, Marcius S.; Almeida, Fabio C. L. . Biomolecular NMR Assignments. https://doi.org/10.1007/s12104-021-10027-6