10th February 2021
Conformational flexibility of GRASP proteins and their constituent PDZ subdomains reveals structural basis of their promiscuous interactome
Luis Felipe Santos Mendes, The University of São Paulo (Brazil)
An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase
Rui Huang, University of Guelph (Canada)
High pressure switches the β1-adrenergic receptor to the active state in the absence of G protein
Layara Abiko, Universität Basel (Switzerland)
24th February 2021
Using Deep Learning for NMR Spectral Reconstruction and Virtual Decoupling
Gogulan Karunanithy, University College London, UK
Characterizing the complex between Lyn kinase and the growth hormone receptor using NMR and molecular simulations
Sowmya Indrakumar, University of Copenhagen, Denmark
Enzyme activity regulation beyond allostery: Substrate discrimination via a proline switch in beta-phosphoglucomutase from Lactococcus lactis
F. Aaron Cruz-Navarrete, University of Sheffield, UK
10th March 2021
NMR-assisted Analyses of Nucleic Acid Therapeutics
Pallabi Sengupta, Quretech Bio, Sweden
Glycan Assignment and Quantification in Microalgae Using in-cell 13C Solid-State NMR
Alexandre Poulhazan, Université du Québec, Canada
A new method for B1 calibration using small molecule CEST
Ahallya Jaladeep, Indian Institute of Science, India
24th March 2021
The dynamical closed state of a bacterial ion channel
Marta Bonaccorsi, ENS-Lyon, France
Two-dimensional reconstruction of distance distributions in pulse dipolar EPR spectroscopy via singular value decomposition
Thomas Schmidt, National Institutes of Health, USA
NMR structural studies of how the proteasome subunit hRpn13 interacts with ubiquitinated substrates and the proteasome
Xiuxiu Lu, National Cancer Institute, USA
7th April 2021
Hsp70 chaperone diversity achieved by Hsp40 class specific regulation
Ofrah Faust, Weizmann Institute, Israel
How accurate is your NMR structure? We have the ANSURR!
Nick Fowler, University of Sheffield, UK
Making sense of cross-correlated relaxation in flexible proteins
Clemens Kauffmann, University of Vienna, Austria
21st April 2021
Oligomeric assembly regulating mitochondrial HtrA2 function as examined by methyl-TROSY NMR
Yuki Toyama, University of Toronto, Canada
Synergistic relationship between water dynamics and functional motions in intrinsically disordered proteins revealed by spin relaxation and molecular dynamics simulations
Nicola Salvi, IBS-CEA Grenoble, France
Protein-drug interactions monitored by time-resolved NMR in human cells
Enrico Luchinat , University of Florence, Italy
5th May 2021
The initial protein oligomeric state dictates the effect of small cosolutes on the domain-swapping reactions within the homeostatic timescale
Borja Mateos, CIC bioGUNE, Derio, Spain
The electrostatic contribution to hydrogen exchange in intrinsically disordered human α-synuclein
Rupashree Dass, Aarhus Uni, Denmark
Characterization of the main protease from COVID-19
Angus Robertson, NIH, USA
19th May 2021
A suite of 19F based relaxation dispersion experiments to assess biomolecular motions
Jan Overbeck, University of Regensburg, Germany
New insights on Hsp40 mediated proteostasis by solution NMR
Theo Karamanos, University of Leeds, UK
Deciphering the intricate code of RG/RGG regions in liquid-liquid phase separation and its regulation by TNPO1
Sinem Usluer, Medical University of Graz, Austria
2nd June 2021
Folding of non-canonical DNA Structures in Real-Time: Insights into G‑Quadruplex Polymorphism
Tassilo Grün, Weizmann Institute of Science, Israel
NMR Metabolomics In Preterm Birth Research
Stella Chasapi, University of Patras, Greece
Room-Temperature DNP NMR Spectroscopy of Small Biological Molecules in Water
Jiafei Mao, University of Frankfurt, Germany
16th June 2021
Influence of binding partners on aggregation of polyglutamine-rich Huntington Exon 1 protein: a quantitative NMR study
Alberto Ceccon, National Institutes of Health, USA
NMR studies of protein conformational transitions induced by high pressure and ligand binding
Jim Xu, City University of New York, USA
Characterization of secondary structure of dehydratase docking domain in complex with dehydratase with MAS NMR
Jacqueline Tognetti, University of Warwick, UK
30th June 2021
Effect of multivalent ions on the phase behaviour of model proteins
Matja Zalar, University of Manchester, UK
Structure and dynamics of nucleosomes with different DNA sequences and histone modifications
Xiangyan Shi, Nanyang Technological University, Singapore
Protein-ligand complex binding pocket structure determination with NMR2, the NMR Molecular Replacement method
Julien Orts, University of Vienna, Austria
14th July 2021
Quantum bioinorganic NMR
Enrico Ravera, University of Florence, Italy
Dynamics of epigenetic DNA modifications by 1H NMR
Romeo Dubini , LMU, Germany
Extending the size limit of DNA systems studied by NMR via a methyl-TROSY approach
Gili Abramov, University of Toronto, Canada
28th July 2021
The role of the intrinsically disordered N-terminal region in the structure and dynamics of Dengue virus capsid protein
Glauce Barbosa, UFRJ, Brazil
Deciphering the paramagnetic NMR spectra of small laccase
Rubin Dasgupta, Karolinska Institute, Sweden
11th August 2021
Atomic level mapping of allosteric pathways controlling non-overlapping functions in the MIF superfamily
George Lisi, Brown University, USA
Studying the allosteric regulation of Mycobacterium tuberculosis ClpP1P2 protease using methyl-TROSY NMR and cryo-EM
Siavash Vahidi , University of Guelph, Canada
Engagement of undergraduate students to expand the RNA chemical shift database
Sarah Keane, University of Michigan, USA
25th August 2021
Global analysis of protein arginine methylation
Fangrong Zhang, Medical University of Graz, Austria
Through-space scalar 19F–19F couplings between fluorinated non-canonical amino acids for the detection of specific contacts in proteins
Henry Orton, The Australian National University, Australia
Structural basis for the activation of the DEAD box helicase DbpA during ribosome biogenesis
Philip Wurm, Uni Regensburg, Germany
8th September 2021
Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with nucleic acids
Icaro P. Caruso, UNESP/UFRJ, Brazil
Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP
Rob Harkness, University of Toronto, Canada
22nd September 2021
The role of conformational entropy in molecular evolution of bacterial transcriptional repressors
Daiana Capdevila, Leloir Insitute, Argentina
Using pulsed EPR and spin labelling to investigate the conformational landscape of integral membrane proteins in lipid bilayers
Christos Pilotas, University of Leeds, UK
Multiple regulatory intrinsically disordered motifs control FOXO4 transcription factor binding and function
Benjamin Bourgeois, Med Uni Graz, Austria
6th October 2021
Monitoring KRAS phosphorylation and mutant-specific GTPase cycling by real-time NMR
Teklab Gebregiworgis, University Health Network, Canada
NMR as a tool to investigate the mechanism of action of (metal)-drugs
Veronica Ghini, University of Florence, Italy
3rd November 2021
Interactions of the disordered N-terminus of the Ral effector
Jasmine Cornish, University of Cambridge, UK
A protein hindered from folding by its parent ribosome
Anais Cassaignau, UCL, UK
24th November 2021
Structural characterization of the RNA-binding protein SERBP1
David Libich, University of Texas – San Antonio, US
Nascent chain dynamics and ribosome interactions within folded ribosome–nascent chain complexes
Charles Burridge, UCL, UK